Fmoc-L-Glutamic acid gamma-methyl ester
Fmoc-L-Glutamic acid gamma-methyl ester
CAS: 145038-50-2
Molecular Formula: C21H21NO6
Fmoc-L-Glutamic acid gamma-methyl ester - Names and Identifiers
Fmoc-L-Glutamic acid gamma-methyl ester - Physico-chemical Properties
| Molecular Formula | C21H21NO6 |
| Molar Mass | 383.39 |
| Density | 1.296±0.06 g/cm3(Predicted) |
| Boling Point | 625.3±55.0 °C(Predicted) |
| Appearance | Powder |
| Color | White |
| pKa | 3.70±0.10(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Physical and Chemical Properties | Storage Conditions: Store at 0-5 ℃ |
Fmoc-L-Glutamic acid gamma-methyl ester - Introduction
Fmoc-L-Glutamic acid gamma-methyl ester is an organic compound with the following properties:
1. Appearance: Fmoc-L-Glutamic acid gamma-methyl ester is a white crystalline solid.
2. Stability: This compound is relatively stable at room temperature.
3. Solubility: Fmoc-L-Glutamic acid gamma-methyl ester is soluble in some organic solvents (such as dimethyl sulfoxide, dichloromethane, etc.).
The main purpose of Fmoc-L-Glutamic acid gamma-methyl ester is to be used as a protecting group in the synthesis of peptides to control the reactivity of amino acids. It can be synthesized:
1. First, dissolve L-glutamic acid in sodium carbonate solution, and then add Fmoc-Cl. After the reaction proceeds, Fmoc-L-glutamic acid can be obtained.
2. Next, methanol and benzylidene chloride were added to the sodium carbonate solution. After the reaction, the Fmoc-L-Glutamic acid gamma-methyl ester can be obtained.
When using the Fmoc-L-Glutamic acid gamma-methyl ester, you need to pay attention to safety precautions:
1. This compound may be irritating to the eyes, skin and respiratory system, so protective measures should be taken when exposed, such as wearing protective glasses, gloves and masks.
2. Avoid inhaling dust or vapor from the solution, as respiratory irritation and discomfort may occur.
3. In use and storage, should be away from the fire and combustible.
4. Waste disposal should comply with local regulations to ensure safety.
1. Appearance: Fmoc-L-Glutamic acid gamma-methyl ester is a white crystalline solid.
2. Stability: This compound is relatively stable at room temperature.
3. Solubility: Fmoc-L-Glutamic acid gamma-methyl ester is soluble in some organic solvents (such as dimethyl sulfoxide, dichloromethane, etc.).
The main purpose of Fmoc-L-Glutamic acid gamma-methyl ester is to be used as a protecting group in the synthesis of peptides to control the reactivity of amino acids. It can be synthesized:
1. First, dissolve L-glutamic acid in sodium carbonate solution, and then add Fmoc-Cl. After the reaction proceeds, Fmoc-L-glutamic acid can be obtained.
2. Next, methanol and benzylidene chloride were added to the sodium carbonate solution. After the reaction, the Fmoc-L-Glutamic acid gamma-methyl ester can be obtained.
When using the Fmoc-L-Glutamic acid gamma-methyl ester, you need to pay attention to safety precautions:
1. This compound may be irritating to the eyes, skin and respiratory system, so protective measures should be taken when exposed, such as wearing protective glasses, gloves and masks.
2. Avoid inhaling dust or vapor from the solution, as respiratory irritation and discomfort may occur.
3. In use and storage, should be away from the fire and combustible.
4. Waste disposal should comply with local regulations to ensure safety.
Last Update：2024-04-09 21:21:28
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View History
Fmoc-L-Glutamic acid gamma-methyl ester
香叶木素-7-新橙皮糖甙
4-(6-CHLORO-3-PYRIDINYL)-3-[(6-CHLORO-3-PYRIDINYL)METHYL]-2-BUTANONE
Benzo[b]thiophene-2-carboxylic acid ethyl ester
N-(2-Hydroxybenzyl)adenosine 5'-(phosphorothioic acid S-methyl) ester
Zirconium, bis[3-(mercapto-κS)-1-propanolato(2-)-κO]-, (T-4)-
H-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH
2,6,6-三甲基-2,4-环己二烯-1-甲酸乙酯
3-氨基-1H-咪唑-1-甲酸叔丁酯
1-(4,6-二甲氧基-2-嘧啶基)-3-[2-(二甲氨基甲酰)-苯氨基磺酰]脲
香叶木素-7-新橙皮糖甙
4-(6-CHLORO-3-PYRIDINYL)-3-[(6-CHLORO-3-PYRIDINYL)METHYL]-2-BUTANONE
Benzo[b]thiophene-2-carboxylic acid ethyl ester
N-(2-Hydroxybenzyl)adenosine 5'-(phosphorothioic acid S-methyl) ester
Zirconium, bis[3-(mercapto-κS)-1-propanolato(2-)-κO]-, (T-4)-
H-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH
2,6,6-三甲基-2,4-环己二烯-1-甲酸乙酯
3-氨基-1H-咪唑-1-甲酸叔丁酯
1-(4,6-二甲氧基-2-嘧啶基)-3-[2-(二甲氨基甲酰)-苯氨基磺酰]脲